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  • SLU-PP-332 Peptide 2 mg – ERR Agonist

SLU-PP-332 is a synthetic pan-agonist of the estrogen-related receptors (ERRα/β/γ), a nuclear receptor family central to mitochondrial biogenesis, oxidative metabolism and exercise-mimetic gene programs. In preclinical models, SLU-PP-332 has been investigated for its ability to enhance mitochondrial function, support fat oxidation and improve endurance and cardiometabolic phenotypes.

The SLU-PP-332 Peptide Pen is configured for The Clinic 2 mL / 200-click pen system, delivering precise 100 mcg-equivalent steps per 10 clicks in a convenient, subcutaneous research format. It is intended for laboratory and educational research use only.

Primary Functions

  • Supports modelling of cellular energy and mitochondrial performance without focusing on muscle loss.

Mechanism of Action & Findings

SLU-PP-332 is a pan-agonist of ERRα, ERRβ and ERRγ. By activating these receptors, it:

  • Engages an aerobic-exercise gene program in preclinical models.
  • Upregulates pathways involved in mitochondrial biogenesis and oxidative metabolism.
  • Enhances cellular respiration and ATP production in animal studies.
  • Supports fat oxidation and cardiometabolic phenotypes in murine models.

As of November 2025, the evidence base for SLU-PP-332 is preclinical only. Published work has been conducted primarily in murine models; no human clinical trials have been completed.

Dosage Protocol — Pen System (Subcutaneous Research Context)

The SLU-PP-332 Peptide Pen uses The Clinic standardised pen system for subcutaneous research dosing. All example values below are expressed in mcg and click counts for clarity.

  • Pen volume: 2 mL
  • Total clicks per pen: 200 clicks
  • SLU-PP-332 content per pen: 2 mg (2000 mcg)
  • Conceptual dose unit: 10 clicks = 100 mcg
  • Implied per-click amount: 10 mcg per click (200 clicks × 10 mcg = 2000 mcg)
  • Route: Subcutaneous injection only (e.g. abdomen or thigh, per lab SOP).

Suggested Dosing – Intro & Standard Phases (SC Models)

Phase Dose per Event (mcg) Clicks per Event Frequency (Example) Notes
Intro / Tolerance (Days 1–3) 100 mcg 10 clicks 2 × daily (morning & evening) Initial response and tolerance mapping.
Standard Phase (Days 4–28) 200 mcg 20 clicks 2 × daily (morning & evening) Mitochondrial and metabolic modelling in SC research.

Pro tip (research context): Many labs conceptually start at 100 mcg (10 clicks) per event, then maintain twice-daily 100–200 mcg exposures for steady-state metabolic and mitochondrial modelling.

How Long the Pen May Last (Approximate)

Pen Content Dose per Event Approx. Events per Pen
2.0 mg (2000 mcg) 100 mcg (10 clicks) ~20 events
2.0 mg (2000 mcg) 200 mcg (20 clicks) ~10 events

Actual usage will vary based on protocol design, model requirements and any deviation from the example framework above.

Expected Outcomes

In preclinical and mechanistic contexts, SLU-PP-332 has been associated with:

  • Mitochondrial optimisation: Upregulation of oxidative metabolism and improved respiration markers.
  • Sustained energy signatures: Exercise-like gene expression and endurance benefits in mice.
  • Fat-oxidation support: Enhanced fat metabolism without compromising lean mass in animal models.
  • Metabolic wellness themes: Favourable cardiometabolic phenotypes in preclinical research.
  • Longevity interest: ERR-linked pathways intersect with energy, mitochondrial quality and metabolic flexibility.

These findings are model- and protocol-dependent and must not be interpreted as guaranteed or therapeutic outcomes in any species.

Use Cases & Exclusions

Typical Use Cases

  • Projects modelling enhanced energy and mitochondrial support.
  • Bioenergetics and performance research focused on ERR signalling.
  • Models targeting safe fat oxidation while preserving lean tissue in animals.
  • Longevity and cellular-wellness concept studies.

Who Should NOT Use

  • Anyone under 18.
  • Pregnant or breastfeeding women.
  • Individuals with serious metabolic or endocrine conditions unless under explicit specialist oversight.
  • Any subject with known allergy or sensitivity to peptides or excipients.

Potential Side Effects & Adverse Signals (Class-Based)

  • Mild injection-site irritation (redness, itching, tenderness).
  • Headache or mild nausea in sensitive models.
  • Temporary restlessness or slight jitteriness.
  • Occasional digestive discomfort.

These are drawn from general peptide experience and early anecdotal reporting; specific SLU-PP-332 human safety data do not exist as human trials have not been completed.


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SLU-PP-332 Peptide 2 mg – ERR Agonist

  • Brand: The Clinic
  • Product Code: SLU-PP-01
  • Reward Points: 32
  • Availability: In Stock

Available Options


Research-Backed Compounds
Precision Pen System
Ongoing Guidance
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