SS31 100mg is a mitochondrial support peptide used to support cellular energy production, heart-focused mitochondrial function, and broader resilience against oxidative stress. It is for people who want stronger support for energy, cardiovascular wellness, cognitive performance, and longevity-focused protocols built around mitochondrial health. Supplied as a 100 mg cartridge in 2 mL, it provides a structured format within The Clinic cartridge system.
SS31 is used when the goal is to support mitochondrial function more directly. By targeting cardiolipin within the inner mitochondrial membrane, it is commonly positioned around energy production, oxidative stress control, heart health, and brain-focused support. The main benefits people look for are better mitochondrial efficiency, improved cellular energy handling, stronger resilience under stress, and broader support for systems that rely heavily on healthy mitochondrial output.
How It Works
SS31, also known as elamipretide, is a mitochondria-targeting peptide that localizes to the inner mitochondrial membrane and binds to cardiolipin. This helps stabilize mitochondrial structure, support more efficient electron transport and ATP production, reduce oxidative stress, and protect against mitochondrial dysfunction. It is most commonly used where the goal is better mitochondrial performance in high-energy tissues such as the heart, skeletal muscle, and nervous system.
| Function |
Primary Effect |
| Cardiolipin support |
Helps stabilize the inner mitochondrial membrane |
| Mitochondrial bioenergetics |
Supports ATP production and more efficient energy output |
| Oxidative stress control |
Helps reduce mitochondrial oxidative stress |
| Cellular resilience |
Supports mitochondrial integrity in high-demand tissues |
| Heart and brain support |
Commonly positioned around tissues with high mitochondrial demand |
Results and Outcomes
SS31 is most strongly positioned for mitochondrial support, energy production, and oxidative stress resilience. It is commonly used where the goal is improved recovery of mitochondrial function, better cellular energy handling, and broader support for heart, brain, and longevity-focused protocols. Heart and cognitive support are logical extensions of its mitochondrial mechanism, while anti-aging use is best understood as a mitochondrial wellness strategy rather than a guaranteed longevity outcome.
| Expected Outcome |
Practical Effect |
| Energy support |
Supports mitochondrial efficiency and cellular energy handling |
| Heart support |
Supports cardiac tissues with high mitochondrial demand |
| Brain and cognitive support |
May assist resilience in energy-demanding neural systems |
| Oxidative stress support |
Supports mitochondrial protection under cellular stress |
| Longevity support |
Supports a broader mitochondrial-health and resilience strategy |
Dosage Protocol
Total strength: 100 mg / 2 mL
Concentration: 50 mg/mL
Cartridge system: 200 units
Per unit: 0.5 mg
Biological half-life: 2-4 hours
Dose strategy: Always use the lowest effective dose
Suggested Dosage Table
| Units |
Dose |
Volume |
| 10 units |
5 mg |
0.10 mL |
| 20 units |
10 mg |
0.20 mL |
| 30 units |
15 mg |
0.30 mL |
| 40 units |
20 mg |
0.40 mL |
Recommended Dosage
| Use Case |
Dose |
Frequency |
Cartridge Equivalent |
| Anti-aging / Longevity |
5-10 mg |
Daily |
10-20 units per dose |
| Energy / Heart Health |
10-15 mg |
2-3 times per week |
20-30 units per dose |
| Brain & Cognitive |
15-20 mg |
2-3 times per week |
30-40 units per dose |
Low, Intermediate and High Dosage Protocols
| Protocol Level |
Dose |
Frequency |
Cartridge Equivalent |
Best Suited For |
| Low |
5-10 mg |
Daily |
10-20 units per dose |
Longevity-focused baseline mitochondrial support |
| Intermediate |
10-15 mg |
2-3 times per week |
20-30 units per dose |
Energy, heart-health, and broader mitochondrial support |
| High |
15-20 mg |
2-3 times per week |
30-40 units per dose |
Higher-demand cognitive and advanced mitochondrial support protocols |
Cycle Guidance
| Phase |
Guidance |
| On-cycle |
Use any of the above protocols for 6-12 weeks depending on need and response |
| Break period |
Break for 4 weeks |
| Repeat |
Repeat if necessary, using the lowest effective dose |
| Interpretation |
SS31 is best run as a defined cycle rather than a continuous maintenance product |
Warnings
| Warning |
Detail |
| Storage |
Keep refrigerated |
| Dose strategy |
Always use the lowest effective dose |
| Cycle duration |
Use for 6-12 weeks, then break for 4 weeks before repeating if needed |
| Positioning |
Best positioned for mitochondrial support, energy, heart health, and resilience-focused use |
Related Products
| Product |
Use Case |
| MOTS-c |
Metabolic and mitochondrial support pairing |
| NAD+ |
Cellular energy and recovery support pairing |
| Glutathione |
Oxidative stress and antioxidant support pairing |
| GHK-Cu |
Cellular recovery and resilience pairing |
